Special Topic: Magnetic Resonance Imaging. Joint meeting of EMBS and the Magnetics Society
Thursday June 18, 2009 6:300PM to 8:00PM
Anschutz Medical Center Education 2 South Building Room L-28-1308 Classroom Map of Campus and Parking: Directions: From E. Colfax, take Fitzsimmons Parkway north to E. 17th Place, Left to Kiowa Lot Visitor Parking, adjacent the Education 2 South Building. Parking is $1 after 6PM Presentation: Quantitative Biomagnetic Imaging. Agenda: 6:30PM - 7:00PM Pizza, Pop, Networking 7:00PM - 8:00PM Presentation by Stephen Russek, Ph.D., followed by Q&A. Date: Thursday, June 18, 2009 Free and Open to All Presenter: Stephen E. Russek, Ph.D., Electromagnetics Division, NIST in Boulder CO Topic: Quantitative Biomagnetic Imaging NIST Programs to Support Quantitative MRI Stephen Russek, Electromagnetics Division, Boulder, CO NIST has recently initiated programs to support quantitative biomagnetic imaging. As part of the International Society for Magnetic Resonance in Medicine (ISMRM) Committee on Standards for Quantitative Magnetic Resonance, NIST is assisting in the design and fabrication of a new system phantom as shown in Fig. 1 (a complete description can be found at http://wiki.ismrm.org/twiki/bin/view/QuantitativeMR/QuantitativeMRWhitePaper2007). This phantom will have features to determine and calibrate: the geometric accuracy of MRI scanners; B0 and B1 non-uniformity; T1, T2, and proton density measurement accuracy; resolution; signal to noise; and system stability. This will be the first MRI phantom that has NIST traceability, open source 3-d models, and an associated numerical imaging phantom and materials properties data base. The phantom will be initially used for quality control during image-based clinical trials, although wide spread clinical implementation is envisioned. Other phantoms are also under development. NIST is working with the Quantitative Imaging Biomarkers Alliance (QIBA) to develop a dynamic contrast enhanced MRI phantom and will be developing susceptibility phantoms and flow/diffusion phantoms. In addition to new MRI phantoms, NIST is developing new measurement systems to characterize advanced MRI nanoagents. These include systems to detect the NMR relaxivity around a single nano-contrast agent; systems to measure the activation of individual nanoagents, and systems to measure magnetic-nanoparticle viral-surrogate concentrations at levels below 104/l. Measurements have been applied to nanoagents, such as that shown in Fig. 2, for which conventional characterization techniques have not been sufficient to understand contrast and functional properties. Presenter Bio Stephen E. Russek obtained an A.B. in physics from Harvard University in 1980, spent several years working at AT&T Bell Laboratories researching silicon device physics, and then obtained a Ph.D. in physics from Cornell University in 1990. His graduate studies at Cornell included in-situ growth of high Tc superconductors and a study of superconducting grain boundary weak-link devices. After graduate school, he was an NRC postdoctoral fellow at NIST in Boulder and worked on characterizing electrical and interface properties of high Tc-normal metal interfaces. He joined the permanent staff at NIST in the Superconductor and Magnetic Measurements Group in January 1992. He currently leads the Magnetic Devices and Nanostructures Project. His research interests include nanomagnetic MRI contrast agents, quantitative MRI, and the development of high-speed spintronic devices. He was the lead investigator on a DARPA-funded Spintronics program, participated in NIST Competence programs on magnetic data storage and magnetic sensors, and was a winner of the Department of Commerce Silver Medal for contributions to spintronic devices. He has been an advisor for over a dozen graduate students and postdocs, a short course instructor for the American Vacuum Society (AVS), and was Chairman of the AVS Magnetic Interfaces and Nanostructures Division. He is a member of the American Physical Society and the International Society for Magnetic Resonance in Medicine. He is author/coauthor of over 100 publications. http://wiki.ismrm.org/twiki/bin/view/QuantitativeMR/QuantitativeMRWhitePaper2007) |
